IMGT Repertoire (RPI)
Gene table: human (Homo sapiens) RPI-MH1Like MICA
Citing this page:Frigoul, A. and Lefranc, M.-P.,
MICA: standardized IMGT allele nomenclature, polymorphisms and diseases,
Recent Research Developments in Human Genetics, 3, 95-145 (2005) ISBN: 81-7736-244-5
with permission from Research Signpost
with permission from Research Signpost
- Fct: FUNCTIONALITY
- F: Functional
- P: Pseudogene
- ORF: Open Reading Frame
- R: Rearranged
- T: Transcribed
- Pr: Translated into protein
"+" or "-" indicates if the gene sequences have been found (+) or not been found (-) rearranged (R), transcribed (T) and/or translated into protein (Pr). Arbitrarily that information is shown on the first line of each gene when the data have been confirmed by several studies.
Functionality is shown between parentheses, (F) and (P), when the accession
number refers to rearranged genomic DNA or cDNA and the corresponding germline
gene has not yet been isolated.
Functionality is shown between brackets, [F] and [P], when the accession number
refers to genomic DNA, but not known as being germline or rearranged.
Click on:
- IMGT gene name to get the corresponding IMGT/GENE-DB entry,
- IMGT allele name to see the corresponding Alignments of alleles,
- accession number to get the corresponding IMGT/LIGM-DB entry.
c: cDNA sequence.
IMGT notes:
- (1) These accession numbers correspond to an artificial assembly of individual exons sequences. These accession numbers are not annotated in IMGT/LIGM-DB as the introns are not sequenced (shown with a succession of 'n').
- (2) The most 3' nucleotide of EX4, which is part of the DONOR-SPLICE, is missing.
- (3) ORF due to one additional nucleotide at the center of the exon 5 leading to a STOP-CODON leading to a truncated protein.
- (4) Incomplete sequence (series of 'n') in EU369697.1 (1497pb, 22/01/08).
- (5) Incomplete intron sequence (series of 'n') in EU365393.1 (1497pb, 16/01/08).
- (6) Incomplete intron sequence (series of 'n') in EU365394.1 (1497pb, 16/01/08).
- (7) Incomplete intron sequence (series of 'n') in AM899996.1 (1257pb, 17/06/08).
- (8) Incomplete sequence (series of 'n') in AM944063.1 (1257pb, 17/06/08).
- (9) ORF due to one additional nucleotide at the center of the exon 5 leading to a STOP-CODON. Partial (5' part of EX4 missing).
- (10) ORF due to one additional nucleotide at the center of the exon 5 leading to a STOP-CODON. Partial (3' part of EX3 and 5' part of EX4 missing).
- (11) Pseudogene due to a DELETION of 172 nucleotides in 5' of G-ALPHA2-DOMAIN leading to a STOP-CODON.
- (12) Partial EX4 in 5'.
- (13) Partial EX2 in 5'.
- (14) Partial EX4 in 5' and EX5 in 3'.
- (15) Incomplete sequence (series of 'n') in EU267602.1 (1485 pb, 30/08/12).
IMGT references:
- [1] Obuchi N. et al., Tissue Antigens, 57, 520-535 (2001). PMID:11556982
- [2] Fodil N. et al., Immunogenetics, 44, 351-357 (1996). PMID:8781120
- [3] Bahram S. et al., Immunogenetics, 44, 80-81 (1996). PMID:8613147
- [4] Wiemann K. et al., J. Immunol., 175, 720-729 (2005). PMID:16002667
- [5] Suzuki Y. et al., Gene, 200, 149-156( 1997). PMID:9373149
- [6] Pérez-Rodriguez M. et al., Tissue Antigens, 55, 162-165 (2000). PMID:10746789
- [7] Yao Z. et al., Eur J Immunogenet., 26, 225-232 (1999). PMID:10331160
- [8] Visser C.J.T. et al., Immunogenetics, 49, 561-566 (1999). PMID:10380704
- [9] Pérez-Rodriguez M. et al., Eur. J. Immunogenet., 29, 35-46( 2002). PMID:11841487
- [10] Petersdorf E.W. et al., Immunogenetics, 49, 605-612 (1999). PMID:10369917
- [11] Hirose T. et al., Unpublished, 1998.
- [12] Pérez-Rodriguez M. et al., Unpublished, 1999.
- [13] Pérez-Rodriguez M. et al., Tissue Antigens, 59, 216-218 (2002). PMID:12074712
- [14] Rueda B. et al., Tissue Antigens, 60, 526-528 (2002). PMID:12542746
- [15] Quiroga I. et al., Tissue Antigens, 63, 466-469 (2004). PMID:15104678
- [16] Quiroga I. et al., Tissue Antigens, 67, 321-325 (2006). PMID:16634869
- [17] Tian W. et al., Genes Immun., 4, 500-505 (2003). PMID:14551603
- [18] Ban G. et al., Unpublished, 2000.
- [19] Zwirner N.W. et al., Unpublished, 2002.
- [20] Strausberg R.L. et al., Proc. Natl. Acad. Sci. U.S.A., 99, 16899-16903 (2002). PMID:12477932
- [21] Yan L. et al., Unpublished, 2008.
- [22] Yan L. et al., Unpublished, 2007.
- [23] Cox S.T. et al., Tissue Antigens, 73, 85-87 (2009). PMID:19140841
- [24] Glas J. et al., Tissue Antigens, 72, 410-411 (2008). PMID:18647364
- [25] Mas V. et al., Unpublished, 2004.
- [26] Gaudieri S. et al., Immunogenetics, 45, 209-216 (1997). PMID:8995188
- [27] Ota T. et al., Nat Genet, 36, 40-45 (2004). PMID:14702039
- [28] Shiina T. et al., Genetics, 173, 1555-1570 (2006). PMID:16702430
- [29] Bahram S. et al., Proc. Natl. Acad. Sci. U.S.A., 91, 6259-6263 (1994). PMID:8022771
- [30] Leelayuwat C. et al., Immunogenetics, 40, 339-351 (1994). PMID:7927538
- [31] Li W.B. et al., Unpublished, 2004.
- [32] Wakamatsu A. et al., Unpublished, 2007.
- [33] Kaur G. et al., Unpublished, 2004.
- [34] Fodil N. et al., Immunogenetics, 49, 557-560 (1999). PMID:10380703
- [35] Komatsu-Wakui M. et al., Immunogenetics, 49, 620-628 (1999). PMID:10369920
- [36] Zhu F. et al., Tissue Antigens, 73, 358-363 (2009). PMID:19317747
- [37] Zhang Y. et al., Hum. Immunol., 62, 620-631 (2001). PMID:11390037
See also (IMGT Scientific chart):
- Created:
- 23/06/2005
- Last updated:
- 22/09/2023
- Authors:
- Emilie Carillon, Elodie Gemrot, Aurélie Frigoul
